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2015 Annual Meeting
Evening Specialty Conference - Cytopathology
Thursday, March 26, 2015 - 7:30pm to 9:30pm
CC Ballroom B
Clinical histories are printed below. For the fastest viewing of virtual slides, click:

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Clinical Summary:

A 58 year old man presents with a 16 mm cyst in the pancreatic tail. The cyst is unilocular with a thick wall and no mural nodule.




Case title: Parotid Mass FNA
Clinical Summary:

58 year old female presenting with an 8-month history of right sided facial swelling first noticed after an upper respiratory tract infection. MRI revealed a 3.2 x 2.2 cm well-circumscribed cystic, partially enhancing mass in the deep lobe of right parotid gland.MRI images of parotid mass

 

Air dried smear low power
Air dried smear low power
High power ThinPrep
High power ThinPrep
High power ThinPrep
High power ThinPrep
High power ThinPrep
High power ThinPrep
Cell block low power
Cell block low power
Cell block high power
Cell block high power
Case title: EBUS FNA of N2 mediastinal lymph nodes in a patient with pT3N1 squamous cell carcinoma.
Clinical Summary:

The patient is a 53 year old women status post left lower lobe lobectomy for a 7.3 cm squamous cell carcinoma with metastasis to left station 10 lymph node (pT3N1, stage IIIA). She is a former smoker with a history of leukemia (ALL) at age 15 treated with chemotherapy (vincristine and prednisone) followed by mediastinal and prophylactic brain radiation, right breast cancer at age 37 (pT1N1mi, stage IIA), thyroidectomy for benign thyroid disease at age 40, and left breast cancer at age 42 (ER+/PR+/Her2-, Elston grade 3,  pT2N0, stage IIA). Three months after her lobectomy she presented with mediastinal lymphadenopathy and underwent an EBUS biopsy of 4L and station 7 lymph nodes.

Diff Quik stained smear of station 7 lymph node (40xX)
Diff Quik stained smear of station 7 lymph node (40xX)
Pap stained smear of station 7 lymph node (400X).
Pap stained smear of station 7 lymph node (400X).
Pap stained smear of station 7 lymph node (400X).
Pap stained smear of station 7 lymph node (400X).
Pap stained smear of station 7 lymph node (400X).
Pap stained smear of station 7 lymph node (400X).
Hematoxylin-eosin stained slide of clot section (400X).
Hematoxylin-eosin stained slide of clot section (400X).
Immunostain for p40 of clot section (400X).
Immunostain for p40 of clot section (400X).
Hematoxylin-eosin stained slide of clot section (400X).
Hematoxylin-eosin stained slide of clot section (400X).
Mucicarmine stained slide of clot section (400X).
Mucicarmine stained slide of clot section (400X).
Immunostain for TTF-1 of clot section (400X).
Immunostain for TTF-1 of clot section (400X).
Case title: Atypical Glandular Cells from a Papanicolaou Test
Clinical Summary:

This 50 year-old female presented with vaginal discharge.  The Pap test contained numerous atypical glandular cells.  Follow-up revealed an enlarged and abnormal "barrel cervix", resulting in a hysterectomy.

A low power view of a large cluster of atypical cells
A low power view of a large cluster of atypical cells
A higher power view showing the "drunken honeycomb" pattern of the cells
A higher power view showing the "drunken honeycomb" pattern of the cells
Two cell groups side-by-side show the variation of nuclear atypia
Two cell groups side-by-side show the variation of nuclear atypia
Comparison with squamous cells shows mild nuclear enlargement
Comparison with squamous cells shows mild nuclear enlargement
Small glandular clusters have a rosette-like architecture reminiscent of AIS
Small glandular clusters have a rosette-like architecture reminiscent of AIS
The cells have a columnar configuration with obvious cell boundaries
The cells have a columnar configuration with obvious cell boundaries
The cells have abundant cytoplasmic mucin
The cells have abundant cytoplasmic mucin
Very low power shows the overall architecture of the lesion
Very low power shows the overall architecture of the lesion
This glandular proliferation shows focally increased atypia (upper left)
This glandular proliferation shows focally increased atypia (upper left)
Small glands with mild nuclear atypia are present deep in the cervix
Small glands with mild nuclear atypia are present deep in the cervix