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2015 Annual Meeting
Evening Specialty Conference - Infectious Disease Pathology
Wednesday, March 25, 2015 - 7:30pm to 9:30pm
CC 304/306
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Case title: Spindle cell tumor - lymphoma vs. infection
Clinical Summary:

40 year old HIV-positive female with liver disease, renal failure, and anemia presents with new onset lymphadenopathy.

Clinical impression: lymphoma vs. infection? 

 

lymph node biopsy (H&E, low power)
lymph node biopsy (H&E, low power)
lymph node biopsy (H&E, high power)
lymph node biopsy (H&E, high power)
Case title: Multiple hepatic masses mimicking malignancy
Clinical Summary:

59-year-old African American man with a diagnosis of chronic lymphocytic leukemia (CLL) presented with pain in the right  hand for 2-3 weeks. He has a history of 6 months of persistent fevers with chills and night sweats. He has lost 50-pound during this time as well. The initial examination was unremarkable, but CT scan/MRI showed numerous mass lesions in the liver. The lesions were seen even better on a positron emission tomography (PET) scan, which revealed multiple intensely hypermetabolic hepatic lesions interpreted as metastases. He underwent liver biopsy, which is shown here.








Case title: A brain lesion suspicious for brain tumor
Clinical Summary:

A 42-year-old man with a history of diabetes mellitus, hypertension, and alcohol use presented with dizziness and headache of 1 day’s duration. During subsequent transport to the hospital, he developed generalized tonic-clonic seizures. On admission to the emergency department, the patient was febrile but hemodynamically stable. The patient left the hospital against medical advice.  He was readmitted to the hospital the following month with a 5-day history of left-sided weakness and dizziness. On physical examination, he was noted to be lethargic, with decreased strength on the left side. The patient was transferred to the intensive care unit and treatment with decadron, mannitol, ceftriaxone, and metronidazole was initiated. On hospitalization day 10, a brain biopsy was performed. 

H&E 10x
H&E 10x
H&E 10x
H&E 10x
H&E 20x
H&E 20x
Gram stain 40x
Gram stain 40x
Steiner silver stain 40x
Steiner silver stain 40x
GMS stain 40x
GMS stain 40x
GMS Stain 40x
GMS Stain 40x
Acid-fast stain 40x
Acid-fast stain 40x
Case title: Breast masses detected as a mammographic abnormality
Clinical Summary:

A 68-year-old woman, formerly from the Philippines, was found to have 2 adjacent masses in the right breast on screening mammography.  The masses were well-circumscribed, lobulated, and measured 1.8 x 1.7 x 1.0 cm in aggregate.  After a 6-month follow-up interval, the 2 masses had increased in size (Figure 1), and a stereotactic core needle biopsy was performed.      







Case title: Young woman with a huge abdominal mass
Clinical Summary:

A 34 year old female presented to hospital with a painful abdomen and a large palpable mass. She reported the mass had grown over several months, that she has lost weight, and that she was feeling very fatigued. No other medical history or surgical history was provided. She reported having had 5 previous pregnancies with 3 living children, the youngest of which was 8 years old. She reports no blood is stool and normal periods. On clincal exam, she was visibly distressed and in severe pain with tachycardia.  A surgical consult determine the need to explore the abdomen for a suspected tumor with possible new bowel perforation.

A low power view.
A low power view.
A high magnification.
A high magnification.
A low power view on special stain
A low power view on special stain
A high magnification of a special stain
A high magnification of a special stain