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2015 Annual Meeting
Evening Specialty Conference - Breast Pathology
Monday, March 23, 2015 - 7:30pm to 9:30pm
CC Ballroom B
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Case title: Spindle cell lesion of the breast
Clinical Summary:

A 48 year-old female presented with a palpable mass in the left upper outer breast. On ultrasound and subsequent MRI, the mass appeared solid and measured 4.7 cm. The patient underwent core needle biopsy, with representative images shown here. Immunohistochemistry performed at an outside institution showed the lesion to be focally positive for CK7 and AE1/AE3, and negative for CD34 and S100 protein.

1-Core Biopsy H&E x100
1-Core Biopsy H&E x100
2-Core Biopsy H&E x100
2-Core Biopsy H&E x100
3-Core Biopsy H&E x200
3-Core Biopsy H&E x200
4-Core Biopsy H&E x200
4-Core Biopsy H&E x200
5-Core Biopsy H&E x400
5-Core Biopsy H&E x400
6-Core Biopsy AE/AE3 x200
6-Core Biopsy AE/AE3 x200
Case title: 59 years old female with a right breast mass
Clinical Summary:

59 years old female with a right breast mass, the mass was painless, and there was no axillary lymphadenopathy.

Mastectomy was  performed.

Case title: The family of 13q14 deletion tumors
Clinical Summary:

54 yr female with a palpable, well circumscribed 4.5 cm low density breast mass

 

Mammogram
Mammogram
Lesion margin
Lesion margin




Clinical Summary:

The patient is a 71 year old woman with a history of invasive ductal carcinoma of the right breast, status post lumpectomy and axillary lymph node dissection four years ago.  The pathology from the lumpectomy and axillary lymph node dissection showed a 2.6 cm, SBR grade 3, ER/PR/HER2 triple negative invasive ductal carcinoma and isolated tumor cells in one of seven lymph nodes.  She completed post-operative chemotherapy (Ariamycin, Cytoxan C and Taxol) and radiation therapy.  On her follow-up, she was noted to have an abnormal MRI with an 8 mm, slightly lobulated enhancing mass anterior to the lumpectomy scar.  She underwent an MRI-guided core needle biopsy for the enhancing mass.  These images are representative of the pathologic findings from the core needle biopsy.






Case title: Invasive mammary carcinoma
Clinical Summary:

A 68 year old woman underwent an ultrasound guided core needle biopsy of a left breast mass she detected herself 1 month prior.