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2015 Annual Meeting
Evening Specialty Conference - Surgical Pathology
Tuesday, March 24, 2015 - 7:30pm to 9:30pm
CC Auditorium
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Case title: Case 1 Surgical Pathology Evening Session
Clinical Summary:

48-year-old white male smoker with history of coronary artery bypass grafting associated with injury to the thoracic duct who presents with a three month history of cough with the production of large mucous plugs (see image).  Sections of the mucous plug were submitted for histologic analysis (see whole slide image). 

Bronchial casts
Bronchial casts
Case title: Malignant neoplasm in the brain in a patient with a history of melanoma and breast carcinoma
Clinical Summary:

A 54 year-old female presented to the emergency department with mental status changes and was found to have a large dural-based brain mass. The patient had a reported history of melanoma and breast cancer. The patient underwent surgical resection of the brain tumor, with representative images shown here. On the basis of the tumor morphology and patient’s history, immunohistochemistry for Sox10 and GATA3 were performed.

1-Brain Mass H&E x100
1-Brain Mass H&E x100
2-Brain Mass H&E x100
2-Brain Mass H&E x100
3-Brain Mass H&E x200
3-Brain Mass H&E x200
4-Brain Mass H&E x200
4-Brain Mass H&E x200
5-Brain Mass H&E x400
5-Brain Mass H&E x400
6-Brain Mass Sox10 x100
6-Brain Mass Sox10 x100
7-Brain Mass GATA3 x100
7-Brain Mass GATA3 x100
Case title: CIC-DUX Sarcoma
Clinical Summary:

33-year-old female who presented with a 6.4 cm slowly enlarging mass in the soft tissue just proximal to the knee.

Case title: Three month-old infant with a lung cyst
Clinical Summary:

These photomicrographs are from an asymptomatic three-month-old male infant who was found to have a multilocular lung cyst on chest computed tomography (CT).  A right lower lobe wedge excision was performed. 

Figure 1. CXR and CT scan
Figure 1. CXR and CT scan
Figure 2. Low power view of right lower lobe lung cyst
Figure 2. Low power view of right lower lobe lung cyst
Figure 3. Low power view of multilocular cystic structure
Figure 3. Low power view of multilocular cystic structure
Figure 4. Low power view of multilocular cystic structure
Figure 4. Low power view of multilocular cystic structure
Figure 6. Medium power view of cyst wall.
Figure 6. Medium power view of cyst wall.
Figure 7. Higher power view of field in Figure 6.
Figure 7. Higher power view of field in Figure 6.
Figure 8. Subepithelial layer of atypical mesenchymal cells
Figure 8. Subepithelial layer of atypical mesenchymal cells
Figure 9. Small subepithelial collection of atypical cells
Figure 9. Small subepithelial collection of atypical cells
Figure 10. Subendothelial atypical spindle cells
Figure 10. Subendothelial atypical spindle cells
Figure 11. Focus of cyst wall necrosis
Figure 11. Focus of cyst wall necrosis
Clinical Summary:
  • 25 year old male, gross hematuria & pain in right chest wall (Sept 2013)

  • CT revealed

    • 12 cm right renal mass with suspicion of direct invasion into the liver

    • Lytic bone metastases - right 7th rib, right humeral head

    • Bilateral small lung nodules, each less than 1 cm

  • Rib mass biopsied (outside institution) – Dx: unclassified renal cell carcinoma

  • No family history of renal cell carcinoma

  • Neoadjuvant combination chemotherapy – cisplatin, gemcitabine & paciltaxel (6 cycles)

  • Right radical nephrectomy  (June 2014)

  • Patient died 3 months afPatient died 3 months after surgeryter surgery

 
 
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